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Cryo-EM

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Application Examples

Cryo-EM allows performing state-of-the-art research related to life Sciences, biotechnology, chemistry and materials science projects:

  • Determination of the spatial structure of proteins, protein complexes, protein-ligand complexes, DNA, RNA and nanoparticles.
  • Imaging of cells and their fragments, viruses and bacteriophages, micelles and liposomes.
  • Characterization of polymers, fibers, nanomaterials and orientation and interaction of liquid crystal molecules.

Click on the photo of the selected structure below to read highlight.

SOLARIS Cryo-EM - highlights
NAR Elongator's reaction scheme v3 Cytochrome MCC figure eIF5A_DHS
The cryo-EM reconstructions for the RecFOR-DNA assembly and the RecFR-DNA and RecOR-DNA subcomplexes of the assembly. E. Michalczyk et al., Molecular Mechanism of Topoisomerase Poisoning by the Peptide Antibiotic Albicidin, Nat Catal 6, 52 (2023). doi: 10.1038/s41929-022-00904-1 Researchers show that an artificial protein structure can be used to precisely arrange gold nanoparticles in three dimensions Structural insights into innate immune evasion in human-infective African trypanosomes